Semikan ranks 151st by electorate among the 184 localities of Adıyaman. The neighborhood has a single ballot box, and 84 voters were registered there for the 2023 parliamentary election.
The neighborhood parts ways with the district as a whole. At the 2023 parliamentary election it went to independents with 61 votes, while across Adıyaman the leading party was AK Parti with 45.3%, leaving independents at 5.9%. In the presidential runoff, 68 of 73 valid votes went to Recep Tayyip Erdoğan; across the district that share was 62.0%. At the 2017 referendum 83 of 83 valid votes were 'yes'; across the district the 'yes' share was 63.8%.
At the 2024 local election the neighborhood went to AK Parti with 19 votes, while Adıyaman as a whole was won by CHP. Turnout at the 2024 local election was 83.3%, 11.0 points above the district average.